Assoc. Prof. Dr. Essa M. Saied is an accomplished scholar whose work spans pharmacology, bioorganic chemistry, and medicinal chemistry, contributing significantly to contemporary drug discovery and therapeutic innovation. His scholarly influence is demonstrated by 2,229 citations across 1,535 documents, 72 published works, and an h-index of 31, reflecting strong global recognition. Assoc. Prof. Dr. Essa M. Saied’s academic trajectory includes rigorous training in chemistry, culminating in advanced graduate studies with a specialization in organic and bioorganic chemistry, where he developed a solid foundation in molecular design, synthetic methodologies, and biochemical mechanisms. His professional journey includes progressive roles in academic and research institutions, where he has contributed to pioneering studies on small-molecule drug development, high-throughput screening, lipid biochemistry, heterocyclic chemistry, and the structural biology of disease-related enzymes. He has collaborated with multidisciplinary teams in developing chemical probes, enzymatic assays, and computational models, integrating experimental and in silico approaches to accelerate drug discovery pipelines. Assoc. Prof. Dr. Essa M. Saied’s research interests encompass synthetic medicinal chemistry, lipid metabolism, molecular modelling, virtual screening, anticancer agents, antiviral strategies, and the mechanistic understanding of bioactive metabolites in human disease. His publications in top-tier journals, including Nature, Angewandte Chemie, Nature Communications, PNAS, and Developmental Cell, highlight the depth and impact of his contributions. In addition to his research achievements, he has been actively involved in scientific reviewing, editorial roles, and mentorship, supporting the professional growth of emerging researchers and contributing to the quality and integrity of scientific publishing. His work bridges fundamental chemical sciences and applied biomedical research, enabling the translation of molecular insights into potential therapeutic strategies. Assoc. Prof. Dr. Essa M. Saied’s continuing efforts aim to expand the frontiers of pharmacological science through innovative chemical tools, mechanistic exploration of lipid pathways, and the development of novel drug candidates. In conclusion, Assoc. Prof. Dr. Essa M. Saied stands as a leading figure in his field, recognized for his impactful research, broad expertise, and sustained commitment to advancing scientific knowledge for global health benefit.

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Featured Publications:

1.Saied, E. M., et al. (2025). Synthesis and multi-target antiproliferative evaluation of novel 1,2,4-triazole-3-thione analogues against breast cancer: In silico and in vitro mechanistic insights. RSC Advances.

2.Saied, E. M., et al. (2025). Exploration of the anticancer efficacy of a novel 1,3-thiazole analog in an Ehrlich ascites carcinoma model: In vivo and in silico insights into hepatorenal protective potentials via modulation of apoptosis, oxidative stress and inflammation. RSC Advances.

3.Saied, E. M., et al. (2025). Mapping stress memory: Genetic and epigenetic insights into combined drought and heat tolerance in barley. Plant Cell Reports.

4.Saied, E. M., et al. (2025). Candidate gene discovery for the biofortification of wheat grains with essential micronutrients for global food security. Cereal Research Communications.

5.Saied, E. M., et al. (2025). Multi-targeted azacoumarin–cyanocinnamate hybrids induce G2/M arrest and apoptosis via tubulin and COX-2/VEGFR modulation: Insights from in vitro mechanistic basis and in vivo validation. RSC Medicinal Chemistry.

6.Saied, E. M., et al. (2025). Editorial: Medicinal chemistry for neglected tropical diseases using in vitro, in vivo, and in silico approaches. [Journal Name Not Provided].

7.Saied, E. M., et al. (2024). Live-cell identification of inhibitors of the lipid transfer protein CERT using nanoluciferase bioluminescence resonance energy transfer (NanoBRET). Angewandte Chemie International Edition.