Zsuzsanna Zsengeller | Medicine and Dentistry | Best Researcher Award

Published on by Phenomenological Research Awards

Dr. Zsuzsanna Zsengeller | Medicine and Dentistry | Best Researcher Award 

Assistant professor at Beth Israel Deaconess Medical Center | United States

Dr. Zsuzsanna Zsengeller is a distinguished medical scientist whose career spans clinical medicine, molecular biology, and translational research. She has established herself as a global leader in the investigation of preeclampsia, mitochondrial dysfunction, and kidney-related disorders. With appointments at world-renowned institutions, she has advanced knowledge in gene therapy, molecular signaling, and maternal-fetal health. Her professional journey demonstrates a seamless integration of clinical insight and laboratory research, producing innovative therapeutic approaches. Through consistent scholarly output, grant leadership, and mentorship of future scientists, Dr. Zsuzsanna Zsengeller embodies excellence in academic medicine and translational science, with her work directly impacting patient health worldwide.

Profile:

Orcid

Education:

Dr. Zsuzsanna Zsengeller earned her Doctor of Medicine degree in General Medicine, followed by a Ph.D. in Medical Science with a strong foundation in microbiology. Her academic path was marked by a commitment to understanding complex disease mechanisms through both experimental and clinical approaches. Her postgraduate training included prestigious postdoctoral fellowships in pulmonary biology and respiratory diseases, where she refined her expertise in molecular and cellular biology. These academic experiences provided the groundwork for her lifelong research into oxidative stress, immune signaling, and vascular biology, ultimately shaping her into a well-recognized expert in mitochondrial and maternal health research.

Experience:

Dr. Zsuzsanna Zsengeller has extensive experience as both a clinician and scientist, having held positions across leading hospitals, research institutions, and industry collaborations. Her work includes significant contributions to pulmonary biology, renal pathology, and preeclampsia research. She has served in roles as staff scientist, senior scientist, consultant, and academic faculty member, currently serving as Assistant Professor of Medicine at Harvard Medical School. Her collaborations with multidisciplinary teams have resulted in advancements in therapeutic strategies for cardiovascular, renal, and maternal health. With experience in academia, industry, and clinical translation, she has built a unique career that bridges discovery and application.

Research Interest:

Dr. Zsuzsanna Zsengeller’s research interests center on the pathogenesis and treatment of preeclampsia, kidney disease, and mitochondrial dysfunction. She investigates redox biology, nitric oxide modulation, and oxidative stress pathways to understand how cellular signaling impacts maternal and fetal outcomes. Her translational studies have examined novel dual-function redox modulators, antioxidants, and mitochondrial-targeted therapies. Beyond maternal health, her work extends into nephrology and cardiovascular disease, with particular focus on mechanisms of APOL nephropathy and endothelial dysfunction. Through advanced molecular techniques and therapeutic modeling, her research seeks to translate laboratory discoveries into clinical strategies, offering hope for improved patient outcomes worldwide.

Awards and Honors:

Dr. Zsuzsanna Zsengeller has been recognized with numerous honors that reflect her leadership in biomedical science and translational medicine. She has received institutional research funding awards, including competitive support for her pioneering work on mitochondrial-targeted antioxidants for preeclampsia therapy. Her contributions have also been acknowledged through awards from scientific societies, highlighting her excellence in poster presentations, mentorship, and innovative project design. Her research projects have consistently received funding from federal agencies and medical foundations, underscoring the clinical relevance and impact of her work. These awards honor her as a trailblazer in developing therapies addressing urgent global health challenges.

Publications:

Title: Development of Diaryl Hydrazones for Alleviation of Mitochondrial Oxidative Stress in Preeclampsia
Year of Publication: 2025
Citation: 1

Title: Gasdermin D deletion prevents liver injury and exacerbates extrahepatic damage in a murine model of alcohol-induced ACLF
Year of Publication: 2025
Citation: 1

Title: A Novel Multi-organ Male Model of Alcohol-induced Acute-on-chronic Liver Failure Reveals NET-mediated Hepatocellular Death, Which is Prevented by RIPK3 Inhibition
Year of Publication: 2025
Citation: 5

Title: Differing sensitivities to angiotensin converting enzyme inhibition of kidney disease mediated by APOL1 high-risk variants G1 and G2
Year of Publication: 2024
Citation: 5

Title: Solvent- and Catalyst-Free Environmentally Benign High Hydrostatic Pressure-Assisted Synthesis of Bioactive Hydrazones and the Evaluation of Their Stability Under Various Storage Conditions
Year of Publication: 2024
Citation: 3

Title: A Novel Dual-Function Nitric Oxide Donor Therapy for Preeclampsia—A Proof-of-Principle Study in a Murine Model
Year of Publication: 2023
Citation: 3

Title: Hepatocyte nuclear factor 4α mediated quinolinate phosphoribosylltransferase (QPRT) expression in the kidney facilitates resilience against acute kidney injury
Year of Publication: 2023
Citation: 8

Conclusion:

Dr. Zsuzsanna  Zsengeller stands as a pioneering physician-scientist whose research has transformed the understanding of oxidative stress, mitochondrial dysfunction, and maternal-fetal disorders. Her leadership in translational medicine continues to advance new therapies that address major public health burdens, particularly preeclampsia and kidney disease. Through groundbreaking research, impactful publications, and mentorship of future leaders, she exemplifies the highest standards of academic and clinical excellence. Her career demonstrates how dedication to discovery can be translated into real-world medical advancements, making her a highly deserving candidate for prestigious recognition in biomedical and clinical research innovation.

Hermann L. Müller | Medicine and Dentistry | Women Researcher Award

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Prof. Dr. Hermann L Muller | Medicine and Dentistry | Women Researcher Award

M.D at Klinikum Oldenburg AöR Medical Campus University Oldenburg | Germany

Prof. Dr. Hermann L. Müller is a distinguished pediatrician and academic leader based in Germany. He currently serves as Professor of Pediatrics and Head of the Department of Pediatrics and Pediatric Hematology and Oncology at Klinikum Oldenburg, part of the European Medical School Oldenburg-Groningen. With a career dedicated to advancing pediatric care, Dr. Müller has made significant strides in pediatric oncology and endocrinology, particularly in the study of childhood craniopharyngioma. His collaborative efforts in multinational clinical trials and leadership roles in international societies reflect his commitment to improving treatment outcomes and quality of life for pediatric patients globally.

Profile:

 Orcid

Education:

Prof. Dr. Hermann L. Müller began his medical training in general pediatrics at the University of Marburg and the University of Würzburg, Germany. He further honed his clinical and research expertise through a prestigious post-doctoral fellowship at Stanford University Medical Center under Prof. Dr. Ron Rosenfeld from 1991 to 1993. Following his time in the U.S., he specialized in pediatric oncology, hematology, endocrinology, and diabetology at the Department of Pediatrics, University of Würzburg. His educational trajectory reflects a deep interdisciplinary foundation that has propelled his pioneering work in pediatric neuro-oncology and endocrinology.

Experience:

With decades of clinical and academic experience, Prof. Dr. Hermann L. Müller has served as a leading figure in pediatric medicine. Since 1999, he has been coordinating major clinical trials, including the German/European craniopharyngioma trials HIT-ENDO and KRANIOPHARYNGEOM 2000/2007, involving over 590 patients across Germany, Austria, and Switzerland. Between 2004 and 2011, he was the speaker for the Craniopharyngioma Subgroup of the International Society of Paediatric Oncology (SIOP). At Klinikum Oldenburg, he leads a team dedicated to pediatric hematology, oncology, and endocrinology, integrating clinical excellence with teaching at the Carl von Ossietzky University of Oldenburg.

Research Interest:

Prof. Dr. Hermann L. Müller’s research is centered on the late effects of pediatric oncological diseases, neuro-endocrinology, and hypothalamic disorders. He has a special focus on craniopharyngioma—a rare brain tumor affecting children—and the associated complications such as hypothalamic obesity and disrupted satiety regulation. His work explores both diagnostic methodologies and therapeutic interventions for these conditions, emphasizing long-term patient outcomes and quality of life. Through clinical trials and translational research, he has significantly advanced the understanding of hypothalamic dysfunction and the neuroendocrine sequelae of childhood brain tumors.

Awards and Honors:

Prof. Dr. Hermann L. Müller’s contributions to pediatric oncology and endocrinology have earned him significant recognition within the scientific community. While specific awards are not detailed in the provided CV, his longstanding leadership in European and international clinical trials, coupled with his role in academic pediatric medicine, underscores his stature as a leading expert. His coordination of landmark studies, such as HIT-ENDO, and representation in global professional societies further attest to his impact. His nomination for an award acknowledges both his scientific rigor and his commitment to improving care for children with complex neuro-oncological conditions.

Publications Top Notes:

Title: Childhood craniopharyngioma: treatment strategies and outcomes

Citations: 498

Year of Publication: 2014

Title: Craniopharyngioma and hypothalamic injury: Latest insights into consequent eating disorders and obesity

Citations: 120

Year of Publication: 2016

Title: Management of Hypothalamic Obesity

Citations: 45

Year of Publication: 2020

Title: Craniopharyngioma a chronic disease

Citations: 11

Year of Publication: 2018

Title: Preoperative staging in childhood craniopharyngioma: standardization as a first step towards improved outcome

Citations: 53

Year of Publication: 2016

Title: A systematic review of cognitive performance in patients with childhood craniopharyngioma

Citations: 66

Year of Publication: 2015

Conclusion:

Prof. Dr. Hermann L. Müller stands as a global authority in pediatric oncology and neuro-endocrinology, with a career marked by innovation, leadership, and compassion. His extensive clinical experience, coupled with an exceptional research portfolio and educational contributions, reflects a lifelong dedication to improving pediatric healthcare. His pioneering studies on craniopharyngioma and hypothalamic disorders have transformed treatment approaches and informed international guidelines. Recognizing his achievements through this award would honor a professional who has profoundly impacted children’s lives and fostered meaningful international collaborations in pediatric medicine.

Ivan Hancco Zirena | Medicine and Dentistry | Lifetime achievement Award

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Prof.Dr.Ivan Hancco Zirena | Medicine and Dentistry | Lifetime achievement Award

post doc at Harvard Medical School, Peru.

Dr. Ivan Hancco Zirena is a distinguished Peruvian physician and researcher specializing in clinical hematology, physiology, and high-altitude medicine. With a rich academic and clinical background spanning multiple continents, Dr. Hancco has carved a niche in understanding human adaptation to hypoxia and extreme environments. Currently serving as a postdoctoral researcher at the Thrombosis and Hemostasis Unit at Harvard Medical School’s Beth Israel Deaconess Medical Center, he contributes to groundbreaking studies on coagulation, red cell physiology, and novel antithrombotic agents.

Profile:

🎓 Educational Background:

Dr. Hancco earned his M.D. from the Universidad Nacional del Altiplano in Puno, Peru (2003), and later specialized in Hematology at Universidad Ricardo Palma, Lima. He pursued advanced studies in France, completing a Master’s in Integrated Biology and Physiology at Université Claude Bernard Lyon 1, followed by a Ph.D. in Physiology at Université Grenoble Alpes. His doctoral thesis investigated hematological responses in high-altitude populations living above 5,000 meters, under the supervision of Dr. Samuel Verges. He is currently completing a postdoctoral fellowship at Harvard Medical School (2023–2025).

💼 Professional Experience:

Dr. Hancco brings extensive experience in both clinical and academic medicine. He has worked in emergency care, hematology units, and cardiovascular rehabilitation in Peru, France, and Spain. His research roles at Laboratoire HP2 (France) and currently at Harvard Medical School (USA) have sharpened his focus on high-impact clinical studies. Additionally, he has provided care to patients with benign and malignant hematologic diseases in military and public hospitals.

Research Interests:

Dr. Hancco’s primary research explores the physiological and hematological adaptations to hypoxia, chronic mountain sickness, erythrocytosis, and cardiovascular and thrombotic responses at high altitudes. His recent work delves into the role of thiol isomerases in hemostasis and thrombosis, with applications in vascular medicine and novel antithrombotic therapies. His interdisciplinary approach bridges physiology, hematology, environmental medicine, and cellular biology.

Teaching Experience:

A passionate educator, Dr. Hancco has taught hematology, physiology, and molecular biology at top Peruvian universities including Universidad de San Martín de Porres, Universidad Científica del Sur, and Universidad Nacional del Altiplano. He has led student research groups, facilitated international exchange programs, and integrated research into medical training. His teaching style fosters critical thinking, debate, and hands-on learning in laboratory and clinical environments.

Skills:

Dr. Hancco is skilled in a wide array of biomedical techniques including flow cytometry, cell culture, platelet aggregation, protein purification, magnetic cell levitation, cytokinesis analysis, microscopy, and complete blood count analysis. These tools have supported his innovative research in hypoxia and hemostasis.

🏅 Recognition and Impact:

Dr. Hancco’s research on chronic mountain sickness and thrombosis has global relevance, particularly for populations living in extreme altitudes. His findings contribute to improved diagnostic and therapeutic strategies for hematological disorders in both high- and low-altitude settings. His work has earned him collaboration with world-renowned institutions and recognition as a rising figure in global hematology and physiology.

Publications:

  • Galloylated polyphenols represent a new class of antithrombotic agents with broad activity against thiol isomerases.
    Journal of Thrombosis and Haemostasis, 2025.

  • Cerebral blood flow in Andean children and adolescents living above 5,000 m.
    Journal of Neurophysiology, 2025.

  • Neurological manifestations associated with exercise at altitude.
    Current Neurology and Neuroscience Reports, 2025.

  • Pain perception threshold in young high-altitude natives after acute exposure to severe hypoxic conditions.
    Oxygen (Basel), 2025.

  • Micro- and macrovascular function in the highest city in the world: A cross-sectional study.
    Lancet Regional Health – Americas, 2024.

  • Performance in the six-minute walking test does not discriminate excessive erythrocytosis patients in a severe hypoxic environment.
    International Journal of Environmental Research and Public Health, 2024.

  • Expedition 5300: Limits of human adaptations in the highest city in the world.
    Journal of Physiology, 2024.

  • Cerebral homeostasis and orthostatic responses in residents of the highest city in the world.
    Scientific Reports, 2024.

  • Lower glycemia levels in subjects with excessive erythrocytosis during the oral glucose tolerance test living in conditions of severe hypoxia.
    Frontiers in Physiology, 2024.

  • Are coagulation profiles in Andean highlanders with excessive erythrocytosis favouring hypercoagulability?
    Experimental Physiology, 2024.