Zsuzsanna Zsengeller | Medicine and Dentistry | Best Researcher Award

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Dr. Zsuzsanna Zsengeller | Medicine and Dentistry | Best Researcher Award 

Assistant professor at Beth Israel Deaconess Medical Center | United States

Dr. Zsuzsanna Zsengeller is a distinguished medical scientist whose career spans clinical medicine, molecular biology, and translational research. She has established herself as a global leader in the investigation of preeclampsia, mitochondrial dysfunction, and kidney-related disorders. With appointments at world-renowned institutions, she has advanced knowledge in gene therapy, molecular signaling, and maternal-fetal health. Her professional journey demonstrates a seamless integration of clinical insight and laboratory research, producing innovative therapeutic approaches. Through consistent scholarly output, grant leadership, and mentorship of future scientists, Dr. Zsuzsanna Zsengeller embodies excellence in academic medicine and translational science, with her work directly impacting patient health worldwide.

Profile:

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Education:

Dr. Zsuzsanna Zsengeller earned her Doctor of Medicine degree in General Medicine, followed by a Ph.D. in Medical Science with a strong foundation in microbiology. Her academic path was marked by a commitment to understanding complex disease mechanisms through both experimental and clinical approaches. Her postgraduate training included prestigious postdoctoral fellowships in pulmonary biology and respiratory diseases, where she refined her expertise in molecular and cellular biology. These academic experiences provided the groundwork for her lifelong research into oxidative stress, immune signaling, and vascular biology, ultimately shaping her into a well-recognized expert in mitochondrial and maternal health research.

Experience:

Dr. Zsuzsanna Zsengeller has extensive experience as both a clinician and scientist, having held positions across leading hospitals, research institutions, and industry collaborations. Her work includes significant contributions to pulmonary biology, renal pathology, and preeclampsia research. She has served in roles as staff scientist, senior scientist, consultant, and academic faculty member, currently serving as Assistant Professor of Medicine at Harvard Medical School. Her collaborations with multidisciplinary teams have resulted in advancements in therapeutic strategies for cardiovascular, renal, and maternal health. With experience in academia, industry, and clinical translation, she has built a unique career that bridges discovery and application.

Research Interest:

Dr. Zsuzsanna Zsengeller’s research interests center on the pathogenesis and treatment of preeclampsia, kidney disease, and mitochondrial dysfunction. She investigates redox biology, nitric oxide modulation, and oxidative stress pathways to understand how cellular signaling impacts maternal and fetal outcomes. Her translational studies have examined novel dual-function redox modulators, antioxidants, and mitochondrial-targeted therapies. Beyond maternal health, her work extends into nephrology and cardiovascular disease, with particular focus on mechanisms of APOL nephropathy and endothelial dysfunction. Through advanced molecular techniques and therapeutic modeling, her research seeks to translate laboratory discoveries into clinical strategies, offering hope for improved patient outcomes worldwide.

Awards and Honors:

Dr. Zsuzsanna Zsengeller has been recognized with numerous honors that reflect her leadership in biomedical science and translational medicine. She has received institutional research funding awards, including competitive support for her pioneering work on mitochondrial-targeted antioxidants for preeclampsia therapy. Her contributions have also been acknowledged through awards from scientific societies, highlighting her excellence in poster presentations, mentorship, and innovative project design. Her research projects have consistently received funding from federal agencies and medical foundations, underscoring the clinical relevance and impact of her work. These awards honor her as a trailblazer in developing therapies addressing urgent global health challenges.

Publications:

Title: Development of Diaryl Hydrazones for Alleviation of Mitochondrial Oxidative Stress in Preeclampsia
Year of Publication: 2025
Citation: 1

Title: Gasdermin D deletion prevents liver injury and exacerbates extrahepatic damage in a murine model of alcohol-induced ACLF
Year of Publication: 2025
Citation: 1

Title: A Novel Multi-organ Male Model of Alcohol-induced Acute-on-chronic Liver Failure Reveals NET-mediated Hepatocellular Death, Which is Prevented by RIPK3 Inhibition
Year of Publication: 2025
Citation: 5

Title: Differing sensitivities to angiotensin converting enzyme inhibition of kidney disease mediated by APOL1 high-risk variants G1 and G2
Year of Publication: 2024
Citation: 5

Title: Solvent- and Catalyst-Free Environmentally Benign High Hydrostatic Pressure-Assisted Synthesis of Bioactive Hydrazones and the Evaluation of Their Stability Under Various Storage Conditions
Year of Publication: 2024
Citation: 3

Title: A Novel Dual-Function Nitric Oxide Donor Therapy for Preeclampsia—A Proof-of-Principle Study in a Murine Model
Year of Publication: 2023
Citation: 3

Title: Hepatocyte nuclear factor 4α mediated quinolinate phosphoribosylltransferase (QPRT) expression in the kidney facilitates resilience against acute kidney injury
Year of Publication: 2023
Citation: 8

Conclusion:

Dr. Zsuzsanna  Zsengeller stands as a pioneering physician-scientist whose research has transformed the understanding of oxidative stress, mitochondrial dysfunction, and maternal-fetal disorders. Her leadership in translational medicine continues to advance new therapies that address major public health burdens, particularly preeclampsia and kidney disease. Through groundbreaking research, impactful publications, and mentorship of future leaders, she exemplifies the highest standards of academic and clinical excellence. Her career demonstrates how dedication to discovery can be translated into real-world medical advancements, making her a highly deserving candidate for prestigious recognition in biomedical and clinical research innovation.

Anna Kakehashi | Medicine and Dentistry | Best Researcher Award

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Assoc.Prof.Dr.Anna Kakehashi | Medicine and Dentistry | Best Researcher Award 

Ph.D., D.M.Sc. at Osaka Metropolitan University Graduate School of Medicine, Japan.

Dr. Anna Kakehashi is a distinguished molecular pathologist and cancer researcher with over two decades of experience in the field of experimental pathology, chemical carcinogenesis, and biomarker discovery. As an Associate Professor at the Graduate School of Medicine, Osaka Metropolitan University, Japan, she has built a formidable career focusing on the mechanisms of liver and pancreatic carcinogenesis, with an emphasis on oxidative stress, DNA damage, and molecular diagnostics. Dr. Kakehashi is widely respected for her scientific rigor, international collaborations, and contributions to cancer prevention and public health research.

Profile:

🎓 Educational Background:

Dr. Kakehashi began her academic journey at St. Petersburg State University, Russia, where she earned her Master of Science in Biology (Biochemistry) in 1995. She later pursued doctoral research at Osaka City University, Japan, obtaining her Ph.D. in Medical Science in 2003. Her multidisciplinary education in biochemistry and medical science laid a strong foundation for her path-breaking research in toxicologic and molecular pathology.

💼 Professional Experience:

Starting her postdoctoral career in 2003, Dr. Kakehashi progressed from a research fellow to an assistant professor, and eventually to her current position as Associate Professor. She has held various key roles at Osaka City University (now Osaka Metropolitan University), contributing to research in pathology and mentoring graduate students. Her academic service includes editorial roles for journals like Cancers (MDPI) and Journal of Medical Laboratory Science.

🧪 Research Interests:

Dr. Kakehashi’s research revolves around the molecular mechanisms of chemical and viral carcinogenesis, particularly in liver (MAFLD/MASH and HCC) and pancreatic cancer. Her expertise includes the identification of novel biomarkers, risk assessment of chemical agents, proteomic and metabolomic profiling, and studying the role of oxidative stress and DNA repair in cancer progression. She is especially noted for her work on the hormesis phenomenon and the evaluation of environmental carcinogens.

🏅 Awards and Honors:

Dr. Kakehashi has been recognized with numerous prestigious awards. These include the Princess Takamatsu Cancer Research Fund Award (2022), the Osaka City Medical Association Award (2018), and the Dean’s Award for Excellence from Osaka City University School of Medicine. Her early-career brilliance was acknowledged through the Japanese Society of Toxicology Young Researcher Award and Toxicological Pathology Presentation Award. These accolades affirm her scientific contributions and leadership in cancer research.

🤝 Collaborations and Affiliations:

Dr. Kakehashi is a proactive collaborator, having worked with institutions in Thailand, Russia, and the USA, including St. Petersburg State University and LyondellBasell Industries. In Japan, she has collaborated with numerous university departments and research institutes on carcinogenesis, biomarker discovery, and nanomaterial safety. She is also a longstanding member and councillor of multiple scientific societies such as the Japanese Cancer Association, Society of Toxicologic Pathology, and Japanese Society for Cancer Prevention.

🌍 Community Engagement:

Beyond the lab, Dr. Kakehashi is deeply committed to gender equity in research. She has actively participated in initiatives by Japan’s Ministry of Education to improve research environments for women and promote work-life balance. Her involvement in national review committees also reflects her leadership in shaping research directions at the policy level.

Publications:

  • “Metabolism and effects of acetoaceto-o-toluidine in the urinary bladder of humanized-liver mice”
    Journal of Toxicologic Pathology, 2025

  • “Nicotine promotes the development of invasive bladder carcinoma in rats”
    Journal of Toxicologic Pathology, 2025

  • “Comparative analysis of the toxic effects on the mouse lung of 4 weeks exposure to the heated tobacco product Ploom TECH+ and 3R4F reference cigarettes”
    Journal of Toxicologic Pathology, 2025

  • “Urinary bladder carcinogenic potential of 4,4′-methylenebis(2-chloroaniline) in humanized-liver mice”
    Toxicological Sciences, 2024

  • “Fullerene and fullerene whisker are not carcinogenic to the lungs and pleura in rat long-term study after 2-week intra-tracheal intrapulmonary administration”
    Archives of Toxicology, 2024

  • “Characterizing the toxicological responses to inorganic arsenicals and their metabolites in immortalized human bladder epithelial cells”
    Archives of Toxicology, 2024

  • “Stromal area differences with epithelial-mesenchymal transition gene changes in conjunctival and orbital mucosa-associated lymphoid tissue lymphoma”
    Frontiers in Oncology, 2024

  • “Evaluation of the mechanisms involved in the development of bladder toxicity following exposure to occupational bladder cancer causative chemicals using DNA adductome analysis”
    Biomolecules, 2024

  • “DNA Methylation Aberrations in Dimethylarsinic Acid-Induced Bladder Carcinogenesis”
    Cancers, 2023

  • “Recent Insights into the Biomarkers, Molecular Targets and Mechanisms of Non-Alcoholic Steatohepatitis-Driven Hepatocarcinogenesis”
    Cancers, 2023 (Review Article)

Abdul Sattar Khan | Medicine and Dentistry | Impactful Researcher Award

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Abdul Sattar Khan | Medicine and Dentistry | Impactful Researcher Award

 Head, Family & Community Medicine Department at  King Faisal University, Saudi Arabia.

Dr. Abdul Sattar Khan is an esteemed medical professional specializing in Family Medicine and Medical Education, currently serving as Associate Professor and Head of the Family & Community Medicine Department at King Faisal University, Saudi Arabia. With over 30 years of experience, he has played pivotal roles in medical education and research, influencing healthcare systems across Pakistan, Saudi Arabia, and beyond. His extensive leadership in curriculum development, quality assurance, and strategic planning highlights his commitment to enhancing medical training. Additionally, Dr. Khan’s work spans clinical research, public health initiatives, and advisory roles, contributing to the betterment of healthcare education and policy.

Profile👤

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Education 🎓

Dr. Abdul Sattar Khan holds multiple prestigious qualifications, including a Fellowship in Family Medicine (FRCGP) from the Royal College of General Practitioners, London, in 2017. He completed his MSc in Medical Education from the University of Dundee, UK, in 2019, and earned his MPH from the University of Karachi in 1995. His educational background also includes diplomas in Medical Education, Quality Assurance, and Leadership, as well as certificates in research management and advanced teaching techniques from global institutions like the University of Colorado and McMaster University. His multidisciplinary education allows him to excel in both clinical practice and medical education.

Experience💼

Dr. Khan’s career spans over three decades in academic and clinical leadership. He has served as Associate Professor and Head of Family & Community Medicine at King Faisal University since 2012. His previous roles include Assistant Professor at Ataturk Public University, Turkey, and a faculty member at Baqai University, Pakistan. He has also worked as a family physician and trainer in Saudi Arabia’s healthcare system. Internationally, he collaborates with the Royal College of General Practitioners, UK, and serves as a mentor and tutor for various postgraduate programs. His diverse roles showcase his ability to lead in both academic and healthcare environments.

Research Interests 🔬

Dr. Khan’s research interests are focused on chronic disease prevention, genetic disorders, precision medicine, and the role of artificial intelligence in healthcare. He is passionate about enhancing medical education, particularly in curriculum development and assessment methods. His research has a strong clinical and societal impact, ranging from genetic factors in diabetes complications to improving the quality of life for people with disabilities. Dr. Khan’s interdisciplinary research approach, combining clinical practice with cutting-edge technology and education methodologies, positions him as a leader in addressing critical healthcare challenges.

Awards and Honors 🏆

Throughout his career, Dr. Khan has received numerous awards and honors, including first prize for his oral presentation at the COAMS 2nd Research & Innovation Day in 2023. He has been awarded scholarships for his Fellowship in Faculty Development from the USA and for his MPH from Baqai University. His contributions to healthcare education and research have earned him recognition from several prestigious institutions, such as the Royal College of General Practitioners, UK. Dr. Khan’s accolades reflect his dedication to advancing medical knowledge and his leadership in family medicine and medical education.

Conclusion 🔚 

Dr. Abdul Sattar Khan is an excellent candidate for the Impactful Researcher Award due to his impressive academic qualifications, leadership roles, and research contributions in family medicine, chronic disease management, and medical education. His commitment to public service and global collaborations further strengthens his candidacy. Focusing on high-impact publications and expanding his leadership in international research could further enhance his profile.

Publications Top Notes 📚

Weight reduction among females undergoing laparoscopic ventral hernia repair: The role of Calcium and Vitamin D3
Almulhim, S.A., Alnaim, M.M., Khan, A.S., Al Abdulqader, A.A., Almulhim, A.S.
Pakistan Journal of Medical Sciences, 2024, 40(5), pp. 922–926
Citation: 0

The impact of coronavirus crisis on human interpersonal relationships among AlAhsa population
Khan, A.S., Alnefaie, B.T., Al-Ali, D.S., Almusallam, S.A., Alghannam, F.N.
Annals of African Medicine, 2024, 23(1), pp. 76–81
Citation: 0

Medical Interns’ Perceptions and Attitudes During the COVID-19 Pandemic: A Qualitative Study
Almaqhawi, A., Khan, A., Albarqi, M., Almulhim, A., Ali, S.I.
Turkiye Klinikleri Journal of Medical Sciences, 2023, 43(1), pp. 112–118
Citation: 0

Earning Engagement via E-health (EEE Project)
Khan, A.S.
Medical Science Educator, 2022, 32(4), pp. 763–764
Citation: 0

Psychological impact of the COVID-19 pandemic on healthcare professionals in the Al Ahsa Region, Saudi Arabia
Almaqhawi, A., Khan, A.S., Albarqi, M., Ali, S.I., Elbarbary, H.S.
Family Medicine and Primary Care Review, 2022, 24(1), pp. 27–31
Citation: 3

Hydroxyurea usage awareness among patients with sickle-cell disease in Saudi Arabia
Alsalman, M., Alkhalifa, H., Alkhalifa, A., Alnaim, A., Khan, A.S.
Health Science Reports, 2021, 4(4), e437
Citation: 4

The potential preventive effect of pregnancy and breastfeeding on multiple sclerosis
Alhomoud, M.A., Khan, A.S., Alhomoud, I.
European Neurology, 2021, 84(2), pp. 71–84
Citation: 5

Screening for depression, anxiety, and obsessive-compulsive disorders among secondary school students in Al-Hasa Region, Saudi Arabia
Khan, A., Alalawi, A., Alalawi, M., Albahrani, M., Alhasawi, F.
Journal of Family and Community Medicine, 2021, 28(1), pp. 28–34
Citation: 4

The impact of e-learning modalities on medical students in KSA during the COVID-19 pandemic
Almulhim, A.Y., Almulhim, S.A., Almulhim, A.A., Khan, A.S.
Journal of Taibah University Medical Sciences, 2020, 15(5), pp. 437–438
Citation: 7

Psychological insulin resistance among type 2 diabetic patients attending primary healthcare centers, Al-Ahsa, Saudi Arabia
Alomran, A., Almubarak, D., Alrashed, B., Khan, A.
Journal of Family and Community Medicine, 2020, 27(3), pp. 192–199
Citation: 5